Helicobacter pylori Infection

Helicobacter pylori Infection

What Is H. pylori?

A bacterium that infects the stomach lining, causing gastritis, ulcers, and increasing cancer risk.

Why Do I Need Testing/Treatment?

You may be tested if you have:

  • Peptic ulcer disease
  • Chronic dyspepsia
  • Family history of gastric cancer

How Should I Prepare?

  • Avoid PPIs for 2 weeks and antibiotics for 4 weeks before testing.
  • Testing: urea breath test, stool antigen, or biopsies during endoscopy.

What Happens During Treatment?

  • 10–14-day antibiotic regimen (clarithromycin-based triple or bismuth quadruple therapy).
  • Continue PPI during therapy.

What Can I Expect Afterwards?

  • Symptom improvement within days.
  • Complete eradication in >85% with first‐line therapy.

Risks & Possible Complications

  • Antibiotic side effects (diarrhea, taste disturbance)
  • Reinfection risk (~1–2%/year)

Follow-Up

  • Confirm eradication with breath or stool test ≥4 weeks post-treatment.
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