An inherited syndrome causing hundreds to thousands of colon polyps and a near-100% risk of colorectal cancer by age 40 if untreated.

Why Do I Need Management?

  • Early detection and prophylactic surgery can prevent cancer.

How Should I Prepare?

  • Genetic testing for APC mutation.
  • Annual colonoscopy beginning at age 10–12.

What Happens During Management?

  • Surveillance: Annual endoscopic removal of polyps.
  • Surgery: Colectomy with ileorectal or ileal-pouch anastomosis when polyp burden is high.

What Can I Expect Afterwards?

  • Lifelong surveillance of the retained rectum or pouch.
  • Nutritional counseling for changes in bowel habits.

Risks & Possible Complications

  • Anastomotic leak (<5%)
  • Pouchitis (10–20%)
  • Fertility concerns in pelvic surgery

Follow-Up

  • Upper-GI endoscopy every 1–3 years for duodenal adenomas.
  • Annual surveillance of pouch or rectal stump.