What Is the Whipple Procedure?

A complex operation removing the pancreatic head, duodenum, gallbladder, and part of the bile duct, with reconstruction of digestive tract continuity.

Why Do I Need It?

Indicated for tumors in the pancreatic head or periampullary region without extensive vessel involvement or metastasis.

How Should I Prepare?

  • Assessment: Detailed imaging (CT/MRI), cardio-pulmonary evaluation.
  • Nutrition: Prehabilitation if malnourished.
  • Fasting: NPO from midnight before surgery.
  • Medication Review: Adjust anticoagulants.
  • Consent: Discuss high complexity and potential complications.

What Happens During the Procedure?

  • Under general anesthesia, abdominal incision (open or pylorus-preserving).
  • Removal of head of pancreas, duodenum, bile duct, gallbladder, and sometimes part of stomach.
  • Reconstruction: pancreaticojejunostomy, hepaticojejunostomy, gastrojejunostomy.

What Can I Expect Afterwards?

  • Hospital Stay: 10–14 days.
  • Diet: NPO until bowel function returns, then liquids to solids over 1–2 weeks.
  • Enzyme & Insulin: Pancreatic enzyme supplements; monitor blood sugar.
  • Rehabilitation: Early mobilization and physical therapy.

Risks & Possible Complications

  • Pancreatic fistula (10–20%)
  • Delayed gastric emptying (20–30%)
  • Bleeding, infection (10–15%)
  • Nutritional deficiencies

Seek help for high fevers, abdominal pain, persistent nausea/vomiting, or signs of infection.

Follow-Up

  • Pathology to inform adjuvant therapy.
  • Regular oncology and surgical clinic visits with imaging every 3 months.